Changes of pulmonary function after bone injury treated with polymethylme-thacrylic bone cement

doi:10.3969/j.issn.2095-4344.2013.25.023

Abstract

Abstract:

BACKGROUND: At present, the polymethylme-thacrylic bone cement filling has been widely used in the treatment of fractures and bone injuries during arthroplasty. The pulmonary function changes caused by polymethylme-thacrylic bone cement filling, especially the elderly bone injury patients, should be prevented and treated actively.
OBJECTIVE: To observe the pulmonary function changes after bone injury treated with polymethylme-thacrylic bone cement filling.
METHODS: Twenty-four patients with fractures and arthroplasty bone injury were selected from the Department of Orthopedics, Daqing Oilfield General Hospital between May 2010 and June 2011. The patients were treated with polymethylme-thacrylic bone cement filling. Vital capacity, forced vital capacity and maximum voluntary ventilation changes were compared after treated for 1 day and 1 week.
RESUTLS AND CONCLUSION: For the patients with fractures and arthroplasty bone injury after treated with polymethylme-thacrylic bone cement filling for 1 day, the vital capacity was (2.45±0.56) L, forced vital capacity was (2.20± 0.39) L and maximum voluntary ventilation was (50.9±23.9) L, which were lower than those after treated for 1 week. Polymethylme-thacrylic bone cement filling can affect the pulmonary function of the patients to some extent, and this change may relate with microvascular embolization caused by bone cement application. So pulmonary embolism should be prevented and treated through strengthen monitoring, and durgs application before and after treatment.

Key words: biomaterials, biomaterial academic discussion, polymethylme-thacrylic, bone cement, bone injury, fracture, arthroplasty, pulmonary function, vital capacity, ventilation

CLC Number:

R318

Guan Ji-kui, Zhao Li, Jiang Yu, Li Ze-bao1 Chao Peng-cheng, Wei Min-jie, Wang Hui, Liu Jian-guo. Changes of pulmonary function after bone injury treated with polymethylme-thacrylic bone cement [J]. Chinese Journal of Tissue Engineering Research, 2013, 17(25): 4727-4732.

Figures/Tables 2

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